Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Swinholide A, Theonella swinhoei
A dimeric dilactone macrolide that is cytotoxic to a variety of cancer cell lines in vitro.
MilliporeSigma™ Calbiochem™ MG-132, ≥95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).
MilliporeSigma™ Calbiochem™ HDL Receptor SR-BI Inhibitor, BLT-1
The HDL Receptor SR-BI Inhibitor, BLT-1, also referenced under CAS 321673-30-7, controls the biological activity of HDL Receptor SR-B. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pancuronium Dibromide
A highly potent competitive antagonist selective for nAChRs (IC50
MilliporeSigma™ Calbiochem™ Myristoylated-FEEERA, mP6
A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor I, STF-083010
The IRE1 Inhibitor I, STF-083010 controls the biological activity of IRE1. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ InSolution™ EZH2 Inhibitor, DZNep
A 25 mM (1 mg/98 μL) sterile-filtered solution of Histone Methyltransferase EZH2 Inhibitor, DZNep in H2O.
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor V, 34-2
The Dynamin Inhibitor V, 34-2 controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Histone Methyltransferase EZH2 Inhibitor, DZNep
Histone Methyltransferase EZH2 Inhibitor, DZNep, CAS 120964-45-6, is a cell-permeable inhibitor of EZH2-mediated trimethylation of K27 on histone H3.
MilliporeSigma™ Calbiochem™ Tiagabine Hydrochloride
A potent uptake inhibitor highly selective for GABA Transport-1 (IC50 = 67nM in vivo
MilliporeSigma™ Calbiochem™ Pifithrin-μ
Pifithrin-μ, CAS 64984-31-2, is a cell-permeable inhibitor of p53 interaction with Bcl-xL and Bcl-2. Inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.
MilliporeSigma™ Calbiochem™ Camptothecin, Camptotheca acuminata
A cell-permeable DNA topoisomerase I inhibitor.
MilliporeSigma™ Calbiochem™ AG 825
A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC50 = 0.35 μM) relative to HER1 (IC50 19 μM) autophosphorylation.
MilliporeSigma™ Calbiochem™ Late Endosome Trafficking Inhibitor, EGA
A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.
MilliporeSigma™ Calbiochem™ Caspase-9 Substrate II, Colorimetric
The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.